Definitionv1
Allostatic load: the cumulative biological wear and
Allostatic load: the cumulative biological wear and measurable physiological costs that the body incurs from chronic, unresolvable stress including elevated cortisol, disrupted sleep architecture, immune suppression, cardiovascular strain, and impaired hippocampal function
Why This Is a Definition
This definition precisely establishes 'allostatic load' by identifying its genus (cumulative biological wear) and differentia (from chronic, unresolvable stress with specific measurable physiological manifestations). It distinguishes it from acute stress by specifying the chronic, unresolvable nature and the specific biological mechanisms involved. The definition is precise enough to distinguish it from general stress or fatigue while being consistent with the scientific literature referenced in the lesson.